sickle cell disease sickle cell disease
Conditions
Interventions
N.A.
Sponsors
Amsterdam UMC
Eligibility
Age
2 Years to 64 Years
Inclusion criteria
Inclusion criteria: • Medical diagnosis of sickle cell disease • Age from 16 years old • Written informed consent.
Exclusion criteria
Exclusion criteria: - Refused informed consent - For heart rate based measurements: medical history of arrhythmias and chronic use of medication affecting the heart rate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary study parameters: - Heart related variables: resting heart rate, heartrate/steps-ratio - Variables of Heart Rate variability (e.g. Standard deviation of the R-Rintervals = SDNN, RMDD, HF, LF/HF-ratio) Primary oucomes: A: Occurrence of Acute Chest Syndrome B: Self-reported painful crises | — |
Secondary
| Measure | Time frame |
|---|---|
| • Length of stay (LOS) • Need of (P)ICU admission • Need of red blood cell transfusion • Need of analgesic or opioids: maximum dose during hospital admission | — |
Countries
Netherlands
Contacts
Public ContactC.J. Fijnvandraat
Amsterdam UMC
Outcome results
None listed