Postoperatief functioneren en kwaliteit van leven Hypotension
Conditions
Interventions
The hypothesis of this study is that a proactive strategy keeps the blood
pressure at a safe margin and avoids dropping below the minimal acceptable
threshold of a MAP of 65 mmHg. The proactive stra
2) a guideline with
suggestions how to keep patients at their target blood pressure.
Patients with a high likelihood of IOH require larger safety margins and thus
higher target blood pressures compa
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Adult patients scheduled for elective non-cardiac surgery under general anesthesia or central neuraxial anesthesia with a scheduled stay at the hospital after surgery of at least one night - i.e. inpatients - will be considered eligible for inclusion
Exclusion criteria
Exclusion criteria: Patients will be excluded when scheduled for low risk surgery, such as ophthalmic surgery, endoscopic gastrointestinal procedures, and (interventional) radiologic procedures. Also all other procedures under 30 minutes and obstetric or organ transplantations will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome of the study is persistent functional disability at six months after surgery, measured with the 12-item WHODAS 2.0 questionnaire | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes for the trial are: functional disability after 30 days (WHODAS 2.0), quality of live after 30 days and six months (EQ-5D-5L questionnaire), six-months mortality, in-hospital mortality, length of hospital stay, and in-hospital complications, i.e. acute kidney injury, myocardial injury, stroke, unexpected admission at the intensive care unit, and postoperative use of non-prophylactic antibiotics. | — |
Countries
Netherlands
Outcome results
None listed