Investigation of the mechanical properties of pathological scars using suction-based Optical Coherence Elastography

Investigation of the mechanical properties of pathological scars using suction-based Optical Coherence Elastography - OCT elastography in pathological scars

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON55099

Enrollment

Registered

2021-05-17

Start date

2021-10-25

Completion date

Unknown

Last updated

2024-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

1. Scars 2. Cutaneous cicatrication

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: * Age: 18 years or older * Competent * Keloid or hypertrophic scar.

Exclusion criteria

Exclusion criteria: * Language barrier * Immature scar/open wounds * Connective tissue disorders (e.g. Marfan, Ehlers Danlos, Cutis Laxa)

Design outcomes

Primary

Measure	Time frame
The main objective of this study is to determine whether OCT-based suction elastometry is a proper tool to quantify elasticity of mature keloid and hypertrophic scars and healthy skin in human subjects.	—

Secondary

Measure	Time frame
What is the concurrent validity of this device? Do the results correlate with the item pliability of the POSAS. Can we use this device for the analysis of pathological scars. Although this device does not differ tremendously from the Cutometer, the feasibility needs to be addressed in this pilot. Are the measurements practical and timely? Does a single measurement provide sufficient data for the quantification of the above mentioned parameters? Can this device be used to measure scar specific differences in epidermal thickness	—

Measure

Time frame

What is the concurrent validity of this device? Do the results correlate with the item *pliability* of the POSAS. Can we use this device for the analysis of pathological scars. Although this device does not differ tremendously from the Cutometer, the feasibility needs to be addressed in this pilot. Are the measurements practical and timely? Does a single measurement provide sufficient data for the quantification of the above mentioned parameters? Can this device be used to measure scar specific differences in epidermal thickness

—

Countries

Netherlands

Outcome results