Prospective seizure prediction in epileptic patients using VOC analysis by electronic nose (pilot)

Prospective seizure prediction in epileptic patients using VOC analysis by electronic nose (pilot) - EPIC study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON55086

Enrollment

Registered

2020-11-30

Start date

2021-05-20

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

convulsions epileptic seizures

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: >= 18 years of age Admitted to SEIN for video-EEG recording Diagnosed with epilepsy High seizure frequency (1 or more per week), or admitted for multiple days of video-EEG as part of epilepsy surgery track with tapering of anti-seizure medication Mentally competent and with no learning disabilities

Exclusion criteria

Exclusion criteria: Recent (

Design outcomes

Primary

Measure	Time frame
To determine the diagnostic accuracy, including an ROC curve, sensitivity and specificity, of exhaled breath analysis by eNose for seizure detection and prediction in epileptic patients. To determine the diagnostic accuracy of body odor analysis by eNose for seizure detection and prediction in epileptic patients.	—

Secondary

Measure	Time frame
To determine the diagnostic accuracy of exhaled breath and body odor analysis by eNose for the discrimination between different types of seizures. To compare intra-individual temporal fluctuations in VOC profiles in interictal, pre-ictal, ictal and postictal state.	—

Countries

Netherlands

Outcome results