Chronic Heart Failure
Conditions
Interventions
CRT candidates will receive device optimization and simultaneous study
measurements directly after device implantation. Patients will undergo invasive
pressure-volume (PV) loop assessment during var
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients need to fulfil the 2013 guideline of the European Society of Cardiology criteria for cardiac pacing and cardiac resynchronisation therapy upon receiving a CRT.
Exclusion criteria
Exclusion criteria: Age 300 ml Other implantable devices than CRT/PM/ICD in the upper body Structural anatomical / congenital cardiac *deviations*
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Volume-time curves obtained during various pacing configurations will be compared between the non-invasive method (HCP) and the invasive method (conductance catheter). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Evaluate derivatives of volume-time curves (i.e. stroke volume, max volume, min volume, 1/3 FFR) and compare these derivatives between different pacing settings and between the HCP volume-time curve and conductance catheter volume-time curve. 2. Assessment of pressure data during different pacing settings and comparison between the invasive pressure measurements (conductance catheter) and the non-invasive pressure measurements (Nexfin) 3. Reconstruction of pressure-volume (PV) loops with Nexfin and HCP data and compare these PV- loops with PV-loops obtained using the conductance catheter. | — |
Countries
Netherlands
Outcome results
None listed