Contractile segment impedance as a marker for active inflammation in eosinophilic esophagitis in children

Contractile segment impedance as a marker for active inflammation in eosinophilic esophagitis in children - CSI-EOE

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON55028

Enrollment

Registered

2020-07-02

Start date

2020-08-31

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal inflammation provoked by food protein

Interventions

None listed

Eligibility

Age

12 Years to 64 Years

Inclusion criteria

Inclusion criteria: Children aged 12-20 years who will undergo an esophagogastroduodenoscopy for the diagnosis or follow-up of EoE.

Exclusion criteria

Exclusion criteria: Inability to speak/understand English (Australia) or Dutch (The Netherlands)

Design outcomes

Primary

Measure	Time frame
Diagnostic test accuracy of CSI to assess active disease or complete remission compared to reference standard (EGD with histology).	—

Secondary

Measure	Time frame
• To establish the change in CSI with changing inflammation • To calculate inter- and intrarater variability of CSI • To establish a cut-off value for (change in) CSI for the presence / absence of EoE • To perform a cross-validation • To assess the patient burden of patients and parents of CSI and esophagogastroduodenoscopy and compare them. • Cost-effectiveness assessment	—

Countries

Netherlands

Outcome results