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Blood collection to study and modulate dendritic cell-driven T cell responses

Blood collection to study and modulate dendritic cell-driven T cell responses - Influencing DCs to control T cells / Ctrl-TbyDC

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON54980
Enrollment
150
Registered
2021-07-09
Start date
2021-06-01
Completion date
Unknown
Last updated
2024-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

met name gezonde vrijwilligers worden geincludeerd. Donoren met een allergie of auto-immuunziekte worden niet uitgesloten allergy Autoimmunity

Interventions

None listed

Sponsors

Amsterdam UMC, locatie AMC
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - age between 18 and 65 year

Exclusion criteria

Exclusion criteria: - ongoing inflammation or infection at time of blood collection - use of immunosuppressive or biological medication within the last 6 month prior to blood collection - active malignancies - subjects who are employees or students at our department

Design outcomes

Primary

MeasureTime frame
This is not directly applicable within our research. Important aspects that we investigate in vitro are: - T cell polarization towards Th1, Th2, Th17, and Treg phenotype. - DC function/activation - neutrophil function/activation

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)