post-contrast acute kidney injury
Conditions
Interventions
None listed
Sponsors
Medisch Universitair Ziekenhuis Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients with eGFR
Exclusion criteria
Exclusion criteria: age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In the context of post-contrast acute kidney injury, change in serum creatinine is the gold standard recommended in all (inter)national guidelines on safe use of iodinated contrast material. The primary outcome of the current study is peak changes in serum creatinine within 5 days from a baseline measurement, determined within prespecified periods (see Section J, Table 1). The effect of contrast administration will be expressed as the mean intra-patient difference in peak changes in serum creatinine between 5-day pre- and post-contrast periods. | — |
Secondary
| Measure | Time frame |
|---|---|
| Other outcomes are peak changes in serum creatinine occurring at 1 month post-contrast compared to those occurring in absence of contrast; time to post-contrast peak change in serum creatinine; incidences of classic and KDIGO definitions of acute kidney injury in absence of contrast compared to post-contrast; changes in eGFR within 5 days from baseline in absence of and post-contrast; change in eGFR at 1-month post-contrast; incidences of eGFR decline >=5 mL/min/1.73m2, dialysis and mortality at 1-month post-contrast; and time to naturally excreted contrast-free urine. Finally, samples will be stored in order to determine serum contrast (patients with retention or | — |
Countries
Netherlands
Outcome results
None listed