anorexia nervosa eating disorder
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
12 Years to 64 Years
Inclusion criteria
Inclusion criteria: Female patients between 13 and 20 years of age (first-time ill) for the first group, and between 18 and 35 years of age (start in adolescence) with AN and atypical AN according to DSM-5 for the second (chronic) patients. Age-matched controls without eating disorder, BMI 20th percentile.
Exclusion criteria
Exclusion criteria: Organic brain disease, psychotic disorder, bipolar disorder, IQ
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome: Differences in MI between short-term ill and long-term ill patients and HC, cross-sectional and longitudinally during weight restoration over 1 year. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes: Changes in MI composition in relation to olanzapine use, locomotor activity, gastrointestinal complaints, eating disorder symptoms, anxiety, mood, neuropsychological inefficiencies, gut permeability, serum inflammation markers, IgG analysis. | — |
Countries
Netherlands
Outcome results
None listed