Skip to content

Cohort study into Mood and Resilience in Offspring - the MARIO study

Cohort study into Mood and Resilience in Offspring - the MARIO study - MARIO cohort study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON54834
Enrollment
1650
Registered
2019-03-26
Start date
2019-11-29
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bipolar disorder Depression

Interventions

None listed

Sponsors

Vrije Universiteit Medisch Centrum
Lead Sponsor

Eligibility

Age
2 Years to 64 Years

Inclusion criteria

Inclusion criteria: - Child is between the age of 10 - 25 years - Children recruited from the BRIDGE study are between the age of 10-32 years - Parent participated in one of the following four cohort studies: NESDA, BiG, OPPER, MOTAR, BINCO or NormQuest. Or child has participated in cohort study BRIDGE or IMAGE_AL - Written informed consent of child and parent (depending on the age of the child) - Fluent in Dutch

Exclusion criteria

Exclusion criteria: - Child is not biological child of the index parent - Subjects with a cognitive impairment, sufficient to interfere with their ability to provide informed consent or complete study questionnaires (based on parent information; IQ

Design outcomes

Primary

MeasureTime frame
- Depression diagnosis via the K-SADS (psychiatric interview) (Kaufman et al., 1997) - Symptoms of depression via the PHQ-9 (Kroenke et al., 2001)

Secondary

MeasureTime frame
- Diagnosis of other types of psychopathology via the K-SADS (Kaufman et al., 1997) - Mania symptoms derived from the screenings items of the K-SADS (Kaufman et al., 1997) and the General Behavior Inventory (Depue et al., 1981) - Dimensional psychopathology via the Adult/Youth Self report (Achenbach & Rescorla, 2001) - Functioning/Impairment based on the fatigue scale of PROMIS (Lai et al., 2013)

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)