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Frailty in uremia: A survey on the effects of CKD 3-5 on physical functioning and -activity, quality of life and nutritional state

Frailty in uremia: A survey on the effects of CKD 3-5 on physical functioning and -activity, quality of life and nutritional state - Frailty in uremia.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON54748
Enrollment
204
Registered
2018-12-17
Start date
2022-12-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease / Kidney faillure

Interventions

none

Sponsors

Universiteit Maastricht
Lead Sponsor

Eligibility

Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Patients: • The population consists of patients attending the predialysis out-patient clinic, in which stage 3-5 CKD is diagnosed. • Age> or equal to 18 years. • Ability to provide written informed consent., Controls: • Age> or equal to 18 years. • Ability to provide written informed consent. • If known with hypertension: well controlled bloodpressure (systolic

Exclusion criteria

Exclusion criteria: Patients: • Inability to provide informed consent • Active symptomatic coronary artery disease or cardiac failure NYHA class III or IV, whitin 3 months before inclusion • Active malignancies, with a life expectancy of less then 1 year • Active infections, whitin 3 months before inclusion CKD after transplantation • For bioimpedance measurements: presence of ICD or pacemaker. There are no restrictions for other measurements in these patients. Controls: • Inability to provide informed consent • Hypertension (with or without the use of hypertensive medication) with a blood pressure higher than 160 mmHg systolic and/or diastolic larger than 100 mmHg during the screening. • Diabetes Mellitus • Self-reported cardiovascular disease / chronic kidney disease

Design outcomes

Primary

MeasureTime frame
The primary objective of the study is to assess the longitudinal effects of differences and changes in renal function at CKD stage 3-5 on physical functioning.

Secondary

MeasureTime frame
The secondary objectives of the study are to assess the longitudinal effects of differences and changes in renal function at CKD stage 3-5 on physical activity, nutritional status, cardiovascular function, quality of life, symptom burden, illness perception, anxiety and depression.

Countries

Netherlands

Contacts

Public ContactE Öztürk

Maastricht Universitair Medisch Centrum +

elife.ozturk@mumc.nl0433875007

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)