Chronic kidney disease / Kidney faillure
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients: • The population consists of patients attending the predialysis out-patient clinic, in which stage 3-5 CKD is diagnosed. • Age> or equal to 18 years. • Ability to provide written informed consent., Controls: • Age> or equal to 18 years. • Ability to provide written informed consent. • If known with hypertension: well controlled bloodpressure (systolic
Exclusion criteria
Exclusion criteria: Patients: • Inability to provide informed consent • Active symptomatic coronary artery disease or cardiac failure NYHA class III or IV, whitin 3 months before inclusion • Active malignancies, with a life expectancy of less then 1 year • Active infections, whitin 3 months before inclusion CKD after transplantation • For bioimpedance measurements: presence of ICD or pacemaker. There are no restrictions for other measurements in these patients. Controls: • Inability to provide informed consent • Hypertension (with or without the use of hypertensive medication) with a blood pressure higher than 160 mmHg systolic and/or diastolic larger than 100 mmHg during the screening. • Diabetes Mellitus • Self-reported cardiovascular disease / chronic kidney disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary objective of the study is to assess the longitudinal effects of differences and changes in renal function at CKD stage 3-5 on physical functioning. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary objectives of the study are to assess the longitudinal effects of differences and changes in renal function at CKD stage 3-5 on physical activity, nutritional status, cardiovascular function, quality of life, symptom burden, illness perception, anxiety and depression. | — |
Countries
Netherlands
Contacts
Maastricht Universitair Medisch Centrum +