psychosis / Post-traumatic stress disorder Schizophrenia
Conditions
Interventions
The PE, EMDR and CR groups will receive a maximum of 16 sessions of treatment.
The third group will be a waiting list group up to the 6-month follow-up, after
which they may choose to receive treatm
Sponsors
Vrije Universiteit
Eligibility
Age
16 Years to 64 Years
Inclusion criteria
Inclusion criteria: • age 16+ years • a lifetime diagnosis of a psychotic disorder in the schizophrenia spectrum, confirmed by the Structured Clinical Interview for DSM-5 (SCID-5) • meeting DSM-5 symptom criteria for PTSD (cluster B to H) on the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) with a minimum score >=23 • willingness to undergo randomisation and a trauma-focused intervention
Exclusion criteria
Exclusion criteria: • changes in antipsychotic or antidepressant medication regimen within 4 weeks before the inclusion interview assessment (to control for medication effects) • insufficient competence in the Dutch language • severe intellectual impairment, defined as an estimated IQ of 70 or less • not being able to travel (or be accompanied) to the outpatient service • not willing or able to learn to use a smartphone
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main outcome is researcher-rated changes in severity of PTSD symptoms on the CAPS between baseline and 6-month follow-up. | — |
Secondary
| Measure | Time frame |
|---|---|
| Researcher-rated presence of PTSD diagnosis, self-rated severity of PTSD and severity of complex PTSD symptoms, posttraumatic cognitions, dissociation, depression, paranoia, auditory verbal hallucinations, social functioning, disruption of social functioning by PTSD symptoms, resilience, personal recovery, sexual functioning, adversities, and revictimization. | — |
Countries
Netherlands
Outcome results
None listed