The relationship between age at menopause loci and the response of controlled ovarian hyperstimulation in women undergoing IVF: a candidate gene study.

The relationship between age at menopause loci and the response of controlled ovarian hyperstimulation in women undergoing IVF: a candidate gene study. - RiSPONS: Risk Score to Predict Outcome of ovariaN Stimulation

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON54409

Enrollment

500

Registered

2020-12-23

Start date

2021-03-18

Completion date

Unknown

Last updated

2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility menopause

Interventions

None listed

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: - A regular menstrual cycle - Undergoing IVF because of male infertility or unexplained infertility - First cycle IVF treatment - Age between 18 and 45 years

Exclusion criteria

Exclusion criteria: - A history of ovarian surgery, chemotherapy of radiation therapy - Non Northern European ethnicity

Design outcomes

Primary

Measure	Time frame
The primary outcome parameter is the responsiveness of the ovaries to exogenous FSH stimulation during IVF treatment, i.e. number of retrieved oocytes.	—

Secondary

Measure	Time frame
Secondary study parameters are other outcomes of the IVF treatment, described by the number of follicles after stimulation, quality of retrieved oocytes, quality of embryo*s as well as pregnancy rate and live-birth rate.	—

Countries

Netherlands

Outcome results