The clinical validation of a dried blood spot method for vancomycin and creatinine

The clinical validation of a dried blood spot method for vancomycin and creatinine - ADVANCED study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON54384

Enrollment

Registered

2021-12-23

Start date

2022-03-21

Completion date

Unknown

Last updated

2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

concentration of antibiotic in blood following infection

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Aged 18 and over - Able to understand written information and able to give informed consent - Treated with vancomycin - Able and willing to undergo a finger prick for dried blood spot sampling - Able and willing to fill in a questionnaire

Exclusion criteria

Exclusion criteria: unable to draw blood samples for study purposes

Design outcomes

Primary

Measure	Time frame
To clinically validate the DBS method for vancomycin and creatinine in comparison to venipuncture vancomycin and creatinine analysis	—

Secondary

Measure	Time frame
- Analyzing the differences in the measured concentrations in the dried blood spot made with blood obtained from venous sampling and capillary sampling. - Evaluating the need of a correction factor and optimizing the correction factor when measuring the hematocrit in the DBS samples - To investigate the patients* experience with the DBS method in comparison to venipuncture	—

Countries

Netherlands

Outcome results