bladder tumor
Conditions
Interventions
Patients will be randomized to either an intervention group or to a usual care
control group (1:1 allocation). The intervention group will receive a
structured multimodal prehabilitation program con
Sponsors
Antoni van Leeuwenhoek Ziekenhuis
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: patients who have histologically confirmed, primary, bladder cancer (cTa-4N0/N+M0)
Exclusion criteria
Exclusion criteria: Patients with severe cognitive or psychiatric disorders; patients who are operated within 3 week; patients with insufficient command of the Dutch language, which precludes them from following study instructions or completing study questionnaires; patients who have contraindications to safely perform exercise training or testing, and; patients who express the intention to follow a similar exercise training programme regardless of randomisation outcome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number of perioperative complications (grade 2 or higher) in the first 90 days following surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| The number of high-grade (grade 3 or higher) complications, length of hospital stay, number of readmissions, improvement over time (pre- to post surgery) in cardiorespiratory fitness, physical functioning, nutritional status and a number of patient-reported outcomes (health-related quality of life, anxiety and depression, fatigue, levels of physical activity), changes in tumor hypoxia and health care costs. | — |
Countries
Netherlands
Outcome results
None listed