patiënten met een levensverwachting van drie maanden of minder, ongeacht hun onderliggend lijden. Patients with a limited life expectancy
Conditions
Interventions
We will evaluate the effect of a weekly (personalized) medication advice on
adequate medication management in patients in the last phase of life provided
by CDSS-OPTIMED. The advice is based on curr
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. The patient is 18 years or over and provides informed consent to participate. 2. The patient is aware that recovering from his/her disease is unlikely, as assessed by the attending physician. 3. The patient is competent to decide about trial participation 4. The patient has a life expectancy of at least two weeks and at most three months, as estimated by an attending physician.
Exclusion criteria
Exclusion criteria: 1. The patient is incapable of filling in a (Dutch) questionnaire (patients may be supported by relatives when filling in the questionnaire).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patients* quality of life two weeks after baseline assessment, as measured by the EORTC QLQ-C15-PAL questionnaire (scale 0 to 100). | — |
Secondary
| Measure | Time frame |
|---|---|
| • Patients* quality of life at day 7, 21, 28, and then every 28 days until death (or as long the patient is able to fill in the questionnaire), as measured by the EORTC QLQ-C15-PAL questionnaire (scale 0 to 100), quality of life question. • Symptoms and the occurrence of potential side effects of continuing or discontinuing medication at day 1-7, 14, 21, 28, and then every 28 days until death, as assessed by the Utrecht Symptoom Dagboek (USD, which is based on the Edmonton Symptom Assessment Scale (ESAS), frequently used in palliative care and available in most electronic patient records; • Blood pressure and glucose level in case of antihypertensives and antidiabetics (continued or discontinued) at day 1-7, 14, 21, 28, and then every 28 days until death; for patients discharged to or staying at home the attending home care service will be asked to perform these measurements; • Thrombo-embolic and bleeding events; • Time spent on discussing the medication with the patient, as registered on a time scale (0-5 minutes, 6-10, 11-15 minutes, etc.); • Health care costs, including medication prescriptions, hospital admissions and in-hospital care; • Medication used until death, as derived from patients* medical records and the pharmacist*s information system; • Survival from the moment of inclusion. | — |
Countries
Netherlands
Outcome results
None listed