Timely identification of cognitive decline in multiple sclerosis (part of the Don*t be late! study)

Timely identification of cognitive decline in multiple sclerosis (part of the Don*t be late! study) - Don't be late! WP1

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON54277

Enrollment

750

Registered

2022-05-04

Start date

2022-07-19

Completion date

Unknown

Last updated

2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

MS Multiple Sclerosis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Confirmed MS diagnosis according to the McDonald 2017 criteria - Age between 18 and 67 - No recent changes in disease modifying therapy (i.e., no changes in last 3 months) - No current relapse or steroid treatment in the six weeks prior to the study visit

Exclusion criteria

Exclusion criteria: - Patients with neurological (other than MS) and psychiatric disorders - A current or history of drug or alcohol abuse - Being unable to speak or read Dutch

Design outcomes

Primary

Measure	Time frame
The main outcome measures are: Sensitivity, specificity, negative and positive predictive value of Multiple Screener© compared to the gold standard (MACFIMS).	—

Secondary

Measure	Time frame
Secondary outcome measures include the test-retest reliability of the Multiple Screener© and the relationships between cognitive functioning (as measured with the Multiple Screener© and the MACFIMS test batter) and psychological, work-related and qualty of life measures. Additionally, the experiences with the discussion and assessment of cognitive functioning are secondary outcome measures.	—

Countries

Netherlands

Outcome results