Longitudinal recordings of local field potentials in movement disorder patients implanted with deep brain stimulation electrodes

Longitudinal recordings of local field potentials in movement disorder patients implanted with deep brain stimulation electrodes - Longitudinal recordings in patients implanted with DBS electrodes

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON54252

Enrollment

Registered

2020-07-08

Start date

2020-09-16

Completion date

Unknown

Last updated

2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

movement disorders shaking

Interventions

Not applicable.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Newly implanted patient with the Medtronic Percept* PC neurostimulator, and diagnosed with Parkinson*s disease, tremor or dystonia (nb this can be during the first DBS lead implantation or during the repacement of the prior DBS neurostimulator). - Informed consent - Age 18 years or older

Exclusion criteria

Exclusion criteria: - Patients implanted with the Medtronic Percept* PC neurostimulator with other other indications than Parkinson's disease, tremor or dystonia - Patients implanted with a Medtronic DBS Pocket Adaptor Model 64001 or 64002. These DBS systems are not compatible with BrainSenseTM technology.

Design outcomes

Primary

Measure	Time frame
Primary end points per study part: Part A: correlation of disease specific neural oscillations ON and OFF stimulation (full-spectrum (0-125 Hz) recordings) with symptom severity. Part B: relation between neural oscillations with DBS switched ON and OFF, their interaction with symptom severity, and their stability during multiple measurements over time. Part C: relation between PD motor and non-motor symptoms, motivational state, smartwatch kinematics and neural oscillations over a 2-week at-home intervalrelation between the presence of disease	—

Measure

Time frame

Primary end points per study part: Part A: correlation of disease specific neural oscillations ON and OFF stimulation (full-spectrum (0-125 Hz) recordings) with symptom severity. Part B: relation between neural oscillations with DBS switched ON and OFF, their interaction with symptom severity, and their stability during multiple measurements over time. Part C: relation between PD motor and non-motor symptoms, motivational state, smartwatch kinematics and neural oscillations over a 2-week at-home intervalrelation between the presence of disease

—

Secondary

Measure	Time frame
-	—

Countries

Netherlands

Contacts

Public ContactM. Beudel

Amsterdam UMC

m.beudel@amsterdamumc.nl020-7327497

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Apr 17, 2026