Affective Disorder Depression
Conditions
Interventions
Patients of the neurofeedback group take part in five neurofeedback sessions
(four weekly sessions and one session four weeks after the fourth session). The
fMRI-NF sessions will include anatomical
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosis of a depressive disorder (ICD-10: F32 or F33) 2. Currently depression (QIDS >= 17) 3. If required to meet recruitment targets the minimum entry score will be reduced QIDS >= 13 (i.e. still corresponding to a moderate level of depression)
Exclusion criteria
Exclusion criteria: 1. Exclusion criteria for MRI (e.g. cardiac pacemaker, certain metallic implants) 2. History of psychotic disorder bipolar disorder, or psychotic depression 3. Current use of illegal drugs (any in the last four weeks) 4. Current excessive alcohol consumption that interferes with daily functioning 5. History of neurological disease that could influence the fMRI signal and/or the ana-tomical alignment (e.g. territorial stroke, multiple sclerosis, brain tumour)6. Scoring a 3 on item 12 of the QIDS (‘thoughts of suicide’), while not currently in treatment (those falling under this category will be advised to contact their GP or other clinical professional to seek clinical help in the first instance).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IDS (Inventory of Depressive Symptomatology) scores at post-intervention between groups | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Scores at post-intervention between groups for: BDI (Beck Depression Inventory) HADS (Hospital Anxiety and Depression Scale) SES (Self Efficacy Scale) QoL (Quality Of Life scale) EQ-5D-5L (EuroQol research foundation questionnaire) PsyMate depression questions 2. Scores after each neurofeedback session in Profile of Mood States (POMS) 3. Neurofeedback performance 4. Changes in brain structure / activation over time 5. Correlations between neurofeedback performance and the other measures at baseline, during the training and post intervention | — |
Countries
Netherlands
Contacts
Public ContactDEJ Linden
Universiteit Maastricht
Outcome results
None listed