Chronic pain
Conditions
Interventions
Injectiin MRI-contrast
Injection 18F-FDG forPET
Bloodsample collection.
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Age between 18 and 75 years - Persisting pain, defined as (more than 3 months) o Hip patient specific: * pain in the hip region after ipsilateral hip prosthesis more than 10 months ago * patients must report an NRS scale of 3 or higher o Low back group specific: * no improvement of symptoms after at least three months of conservative treatment according to the Dutch guidelines for non-specific low back pain (GP care (advise to stay active and pain medication) and exercise therapy) in primary care. * patients must report an NRS scale of 6 or higher * in case of prior surgery: at least 10 months ago - Eligible to undergo 18F-FDG PET/MRI - Capable to participate in the study
Exclusion criteria
Exclusion criteria: - Contra-indications for 18F-FDG PET/MRI (e.g. metallic foreign bodies, etc.) - Known renal insufficiency; - Known allergy to contrast agents - Prior spinal fusion - BMI *35 kg/m2 - Cancer - Opioid addiction - Metabolic disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain reduction on an NRS scale between patients receiving standard clinical care versus patients receiving additional 18F-FDG PET/MRI guided treatment | — |
Countries
Netherlands
Outcome results
None listed