hearing impairment hearing loss
Conditions
Interventions
None listed
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Aged 18-70 years (pilot studies) or aged 35 - 75 years (main study), - native speaker of Dutch, - normal or corrected-to-normal eyesight, - age-normal hearing (ISO 7029, 2017) for normal hearing participants OR - worse than age-normal hearing for non-congenital hearing impaired participants OR - having received a CI at least 1 year before, for CI users.
Exclusion criteria
Exclusion criteria: - Currently suffering from a severe neurological or psychiatric disease, - Use of psychoactive drugs - Use of drugs influencing ANS activity (e.g. β-blockers, cholinergic agents), - Medication influencing skin or cardiac SNS activity (hyperhidrosis related (e.g. glycopyrrolate ), cardiac related (e.g. beta-blockers) or antidepressants (e.g. SNRIs)) - Metabolic disorders: uncontrolled thyroid and/or adrenal disease - Alcohol abuse defined as: for men > 21 units/week, for women > 14 units/week - Serious heart, pulmonary, hepatic or renal diseases/impairment, malignant or haematological disease - Diagnosed neuropathy - Having (eye-)diseases influencing the pupil response such as diabetes mellitus and cataract.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters of this study include: 1) the pupil response parameters as collected in the laboratory test session: the peak pupil dilation response, principal component analyses parameters and growth curve analysis parameters 2) the physiological measures collected in the ambulatory part of Experiment 1 and 3 by the VU-AMS, including the indices of SNS activity: Pre-Ejection Period (PEP), Skin Conductance Level (SCL), non-specific Skin Conductance Response (nsSCRs), indices of PNS activity: Respiratory Sinus Arrhythmia (RSA), Root Mean Square of Successive Differences (RMSSD), and Heart-Period (HP). 3) the answers to the EMA questions in Experiment 1 and 3 (17 to 23 Likert scale ratings about affective state, ongoing (social)activity, and listening conditions, see F.1 vragenlijst ambulante metingen), in combination with the six acoustical features extracted by the microphone set-up: the binaural root mean square [RMS] loudness level, 2) the zero-crossing rate of the signal and its first derivative, 3) the smoothed power spectral density and 4) cross power spectral densities, the 5) smoothed Mel Frequency Cepstral Coefficients and 6) the signal envelope. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) performance and six subjective Visual Analogue Scale (VAS) ratings collected in the speech perception in noise test 2) performance, pupil response parameters, subjective ratings and VU-AMS data collected during the Paced Visual Serial Addition Test (PVSAT) test (Experiment 1 and 3) 3) questionnaire data (subjective hearing difficulties, coping with hearing loss, hearing and work, and need for recovery) 4) data automatically stored by the smartphone application, such as movement data, temperature, illumination level, pedometer (Experiment 1 and 3). | — |
Countries
Netherlands
Outcome results
None listed