LIfelong Fitness Testing: The Steep Ramp Test in Dutch adults and elderly: age- and sex-related normative values and the investigation of reproducibility, validity, and underlying physiological responses.

LIfelong Fitness Testing: The Steep Ramp Test in Dutch adults and elderly: age- and sex-related normative values and the investigation of reproducibility, validity, and underlying physiological responses. - LIFT - Normative values for the Steep Ramp Test in adults and elderly

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON54149

Enrollment

720

Registered

2021-12-21

Start date

2022-03-14

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

geen, het betreft gezonde proefpersonen nvt

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Healthy Dutch (living in the Netherlands and/or having a Dutch passport) adults, including elderly, aged between 25-85 years.

Exclusion criteria

Exclusion criteria: Subjects who meet any of the following criteria will be excluded: - A medical status (physically or mentally) that contraindicates maximal exercise, based on the PAR-Q (all questions need to be answered with ); - Not compliant with the Dutch physical activity guidelines (a minimum of 5 days a week, 30 minutes a day moderate-to-vigorous physical activity), based on the SQUASH; - The use of medication affecting exercise capacity; - Evident health conditions affecting exercise capacity; - Impaired motor development; - Obesity (body mass index >30 kg/m2); - Unable to cooperate with the testing procedures (e.g. insufficient understanding of the Dutch language); - Being an elite athlete (>= 10 hours a week high physically active); - Pregnancy.

Design outcomes

Primary

Measure	Time frame
WRpeak (in W en W/kg) attained at the SRT	—

Secondary

Measure	Time frame
For all subjects: - Age (years) - Sex (male/female) - Body height (cm) - Body mass (kg) - Lean body mass (kg) - Fat percentage (%) - Waist and hip circumference (cm) - Habitual physical activity (score on the SQUASH) - Overall health status (score on the EQ5D+C) - Heart rate in rest (bpm) - Heart rate at peak exercise (bpm) - Duration of the test (s) Additionally, for group 2: - WRpeak (W en W/kg) attained at an additional SRT performed within one to two weeks after the initial SRT Additionally, for group 3: - Maximal isokinetic upper leg muscle strength (peak torque in Nm) - Upper leg muscular endurance o % decline between first and last repetition o Time (number of repetitions) to x% decline o Area under the curve (to assess the course of the decline in strength) - Parameters for CPET and SRT with respiratory gas analysis, electrocardiography and blood pressure assessment: o Absolute oxygen uptake (ml/min) at rest and at peak exercise o Relative oxygen uptake (ml/min/kg) at rest and at peak exercise o Minute ventilation (VE) (L/min) at rest and at peak exercise o Breathing frequency (breaths/min) at rest and at peak exercise o Tidal volume (Vt) at rest and at peak exercise o Oxygen pulse (ml/beat) at peak exercise o Absolute work rate (W) at peak exercise o Relative work rate (W/kg) at peak exercise o Heart rate (bpm) in rest and at peak exercise o Blood pressure (mm/Hg) at rest and throughout progressive exercise o Oxygen saturation (SpO2) (%) at rest and at peak exercise o Respiratory exchange ratio (RER) at peak exercise o Test duration (s) o Ventilatory anaerobic threshold (VAT) o Oxygen uptake efficiency slope (OUES) o Minute ventilation/carbon dioxide production slope (VE/VCO2) up to the respiratory compensation point o Ratio of the increase in oxygen uptake to the increase in work rate o Rate of perceived extension (RPE) at rest and at peak exercise o Stop reason For CPET only, the forced expiratory volume (FEV1)	—

Measure

Time frame

For all subjects: - Age (years) - Sex (male/female) - Body height (cm) - Body mass (kg) - Lean body mass (kg) - Fat percentage (%) - Waist and hip circumference (cm) - Habitual physical activity (score on the SQUASH) - Overall health status (score on the EQ5D+C) - Heart rate in rest (bpm) - Heart rate at peak exercise (bpm) - Duration of the test (s) Additionally, for group 2: - WRpeak (W en W/kg) attained at an additional SRT performed within one to two weeks after the initial SRT Additionally, for group 3: - Maximal isokinetic upper leg muscle strength (peak torque in Nm) - Upper leg muscular endurance o % decline between first and last repetition o Time (number of repetitions) to x% decline o Area under the curve (to assess the course of the decline in strength) - Parameters for CPET and SRT with respiratory gas analysis, electrocardiography and blood pressure assessment: o Absolute oxygen uptake (ml/min) at rest and at peak exercise o Relative oxygen uptake (ml/min/kg) at rest and at peak exercise o Minute ventilation (VE) (L/min) at rest and at peak exercise o Breathing frequency (breaths/min) at rest and at peak exercise o Tidal volume (Vt) at rest and at peak exercise o Oxygen pulse (ml/beat) at peak exercise o Absolute work rate (W) at peak exercise o Relative work rate (W/kg) at peak exercise o Heart rate (bpm) in rest and at peak exercise o Blood pressure (mm/Hg) at rest and throughout progressive exercise o Oxygen saturation (SpO2) (%) at rest and at peak exercise o Respiratory exchange ratio (RER) at peak exercise o Test duration (s) o Ventilatory anaerobic threshold (VAT) o Oxygen uptake efficiency slope (OUES) o Minute ventilation/carbon dioxide production slope (VE/VCO2) up to the respiratory compensation point o Ratio of the increase in oxygen uptake to the increase in work rate o Rate of perceived extension (RPE) at rest and at peak exercise o Stop reason For CPET only, the forced expiratory volume (FEV1)

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Countries

Netherlands

Outcome results