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IMPRESS: predictors of daily life resilience in advanced cancer patients

IMPRESS: predictors of daily life resilience in advanced cancer patients - IMPRESS

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON54145
Enrollment
70
Registered
2021-12-03
Start date
2022-01-18
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

distress symptoms Psychological distress

Interventions

None listed

Sponsors

Universiteit van Tilburg
Lead Sponsor

Eligibility

Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: - diagnosed with stage IV melanoma with confirmed response to or long-term stable disease while on immunotherapy; - or stage IV lung cancer with confirmed response to or long-term stable disease while on immunotherapy or targeted therapy. We consider a response confirmed after the second scan shows that patients respond well (i.e. RECIST at least partial response or >1 year of stable disease) to one of both therapies.

Exclusion criteria

Exclusion criteria: -

Design outcomes

Primary

MeasureTime frame
A week before participants start with ESM, they will complete several baseline questionnaires. During a two-week period participants are asked to complete ESM eight times per day via an app on their phone. Positive affect, negative affect, daily life events, predictors (i.e. fatigue, pain, emotion regulation and coping), and contextual predictors (i.e. location and company) will be measured in these ESM items. Analyses will be conducted separately for two resilience outcomes (recovery and reward experience). For each model, potential predictors (baseline predictors, momentary predictors, contextual predictors) will be entered as moderators.

Secondary

MeasureTime frame
The secondary objective in this study is to explore whether reward response despite adversity (i.e. advanced cancer diagnosis) predicts low psychosocial distress (symptoms of depression and anxiety) and more illness acceptance, tolerance of uncertainty, mindfulness, optimism and perceived social support a year after measuring resilience in daily life. To explore this, participants will complete a follow-up questionnaire approximately a year after completing the ESM items. This questionnaire contains items about psychosocial distress, illness acceptance, tolerance of uncertainty, mindfulness, optimism, and perceived social support.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)