Preoperative prediction of postoperative physical function, at 6 weeks, in patients with total knee arthroplasty based on physical fitness and patient characteristics; a prospective cohort study

Preoperative prediction of postoperative physical function, at 6 weeks, in patients with total knee arthroplasty based on physical fitness and patient characteristics; a prospective cohort study - Preoperative prediction of postoperative physical function in TKA patients.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON54116

Enrollment

220

Registered

2022-07-22

Start date

2022-10-25

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gewrichts-aandoeningen Knee Osteoarthritis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients will be included if: - They are scheduled for a primary TKA - They are able to perform the preoperative assessment - They are able to fulfill the KOOS by phone 6 weeks postoperatively

Exclusion criteria

Exclusion criteria: Patients will be excluded if: - They get a hemi-knee or revision surgery - They get a primary TKA not due to osteoarthritis of the knee - They weren't able to perform the preoperative assessment - They weren't able to fulfill the KOOS by phone 6 weeks postoperatively

Design outcomes

Primary

Measure	Time frame
The primary outcome is postoperative physical function (KOOS) 6 weeks after TKA surgery. Predicted by physical fitness and patient characteristics measured during the preoperative assessment. The KOOS is a measurement tool to assess physical recovery of knee function. It evaluates both short and long-term outcomes and consists out of 42 items dived in 5 subscales; - Pain - Symptoms - ADL - Sport-recreation - Quality of life (QoL) Determinants: Numeric rating score (NRS) Pain score 0-10 A higher score indicates more pain. 30sec Timed Chair Stand Test (30secTCST) Lower extremity strength More repetitions indicate a better strength. Counts the repetitions of making the transfer from sit to stand during 30 seconds. 2 minute walking test (2MWT) Walking ability A longer distance (meters) indicates a better walking ability. Self-paced walking ability and functional capacity test. Timed up and go test (TUG) Walking ability and balance A shorter time indicates a better walking ability and balance during de transfer from sit to stand and walking 3 meters. Hand grip strength (HGS) Strength Strength in kilogrammes. Measures maximal hand grip strength with the JAMAR dynamometer. De Morton Mobility Index (DEMMI) Activities The higher the score, the better the activities. Measures performing activity tasks independently. Besides the primary outcome and determinants several other relevant study parameters will be collected which describe the characteristics of the participants, like age, sex, body mass index (in kg/m2). Comorbidity will be recorded using the American Society of Anesthesiologists (ASA) classification (I-IV, a higher score indicates less fit for surgery).	—

Measure

Time frame

The primary outcome is postoperative physical function (KOOS) 6 weeks after TKA surgery. Predicted by physical fitness and patient characteristics measured during the preoperative assessment. The KOOS is a measurement tool to assess physical recovery of knee function. It evaluates both short and long-term outcomes and consists out of 42 items dived in 5 subscales; - Pain - Symptoms - ADL - Sport-recreation - Quality of life (QoL) Determinants: Numeric rating score (NRS) Pain score 0-10 A higher score indicates more pain. 30sec Timed Chair Stand Test (30secTCST) Lower extremity strength More repetitions indicate a better strength. Counts the repetitions of making the transfer from sit to stand during 30 seconds. 2 minute walking test (2MWT) Walking ability A longer distance (meters) indicates a better walking ability. Self-paced walking ability and functional capacity test. Timed up and go test (TUG) Walking ability and balance A shorter time indicates a better walking ability and balance during de transfer from sit to stand and walking 3 meters. Hand grip strength (HGS) Strength Strength in kilogrammes. Measures maximal hand grip strength with the JAMAR dynamometer. De Morton Mobility Index (DEMMI) Activities The higher the score, the better the activities. Measures performing activity tasks independently. Besides the primary outcome and determinants several other relevant study parameters will be collected which describe the characteristics of the participants, like age, sex, body mass index (in kg/m2). Comorbidity will be recorded using the American Society of Anesthesiologists (ASA) classification (I-IV, a higher score indicates less fit for surgery).

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Secondary

Measure	Time frame
N.A.	—

Countries

Netherlands

Outcome results