3D joint space evaluation in knee osteoarthritis: The importance of weight-bearing and flexion

3D joint space evaluation in knee osteoarthritis: The importance of weight-bearing and flexion - Weight-bearing and flexed MRI in knee OA

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON54070

Enrollment

Registered

2023-04-28

Start date

2023-11-22

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteoarthritis

Interventions

None listed

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: - Patients with symptomatic knee osteoarthritis in at least one knee - > 18 years old - Kellgren-Lawrence grade (severity) 2 or 3 - Good knowledge of the Dutch language - Signed informed consent

Exclusion criteria

Exclusion criteria: - Previous surgery in (both) symptomatic knee(s) - Inability to stand for 15 minutes, without assistance - Unable to fit knee in the MRI coil (knee width > ~15 cm) - Not eligible for MRI, in response to the MRI safety checklist

Design outcomes

Primary

Measure	Time frame
The primary study parameter is the change in median medial joint space width between the different positions (weight-bearing/non-weight-bearing and flexion/extension).	—

Secondary

Measure	Time frame
Secondary study parameters are: 1. Median lateral joint space width 2. Joint space shift size and direction 3. Change in distance distribution	—

Countries

Netherlands

Outcome results