Respiratory infections
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
No minimum to 11 Years
Inclusion criteria
Inclusion criteria: Age older than 6 weeks and less than 4 years AND 1) have older siblings or 2) attend daycare. AND Live within 30 minutes drive from UMCU (by car) and have access to a fever thermometer
Exclusion criteria
Exclusion criteria: recurrent respiratory tract infections and are treated with antibiotic profylaxis OR known immunodeficiency OR chronic lung disease that increases susceptibility to infection (e.g. cystic fibrosis) OR congenital anomalies of the airways Parents/guardians have insufficient comprehension of Dutch language (all study communication and questionnaires are in Dutch language) A sibling already participating in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| (Co-)occurrence, timing and virus species of respiratory infection as detected by PCR analysis of weekly nasal swab specimens. | — |
Secondary
| Measure | Time frame |
|---|---|
| Presence and severity of respiratory and systemic symptoms compatible with virus infection. Occurrence of acute respiratory illness (ARI) is based on daily symptom monitoring. | — |
Countries
Netherlands
Outcome results
None listed