delirium hip fracture
Conditions
Interventions
The addition of 100 mcg morphine to the intrathecal injection for spinal
anesthesia.
Sponsors
Maasstadziekenhuis
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Proximal femur fracture Scheduled for surgerical treatment Spinal anesthesia
Exclusion criteria
Exclusion criteria: Contraindications for spinal anesthesia: - Coagulation disorders (clopidogrel, INR>1.8, anticoagulation with nadroparine (>100 aXa-IE/kg) or heparine (APTT> 30 sec), recent use of a Direct Oral Anticoagulant, as stated in the guideline *Neuraxisblokkade en antistolling* by the Dutch Society of Anesthesiology. - Aortic Valve Stenosis of AVA 1 month daily use). Other: - Allergies to amide-type local anesthetics and morphine. - Patients* refusal - Patients who are incapable of making decisions regarding anesthesia and no legal representative is available.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of delirium during hospital admission | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are o Delirium Observation Screening Scale (DOSS)-scores (three times daily), o pain scores on a Numeric Rating Scale (NRS), o post-operative opioid consumption, o post-operative consumption of ondansetron for nausea or pruritus, o Patient questionnaire with the Quality of Recovery-15 on POD 1 (including subscales), o Pruritus-severity score on POD 1, o time of mobilization after surgery, o occurrence of complications such as infections, cerebrovascular disorders, respiratory insufficiency and myocardial injury, o mortality, o discharge facility, o length of hospital stay. Tertiary outcome is the serum level of NFL on the second post-operative day. | — |
Countries
Netherlands
Outcome results
None listed