Targeting suicidality in young adults: a randomized, controlled pragmatic, multicentre trial evaluating the (cost)-effectiveness of Attachment Based Family Therapy compared to Treatment as Usual

Targeting suicidality in young adults: a randomized, controlled pragmatic, multicentre trial evaluating the (cost)-effectiveness of Attachment Based Family Therapy compared to Treatment as Usual - REPAIR study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON53903

Enrollment

Registered

2023-06-05

Start date

2023-10-05

Completion date

Unknown

Last updated

2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Suicidality

Interventions

Attachment Based Family Therapy (ABFT): ABFT is a manualized treatment, that emerges from interpersonal theories that suggest suicide can be precipitated, exacerbated, or buffered against by the qua

Eligibility

Age

16 Years to 64 Years

Inclusion criteria

Inclusion criteria: Participants are suicidal young adults and their family. The young adults are between 16 and 30 years old and seek mental health treatment. Participants will be recruited from 16 participating sites. Eligible participants meet the following inclusion criteria: a) Aged between 16 and 30; b) have a score of 31 or more on the SIQ-JR (the cut-off for suicidality); c) have at least one primary parent or caregiver that participates in the assessment and treatment. This could be a biological parent, stepparent, grandparent, other relative, or a foster parent.

Exclusion criteria

Exclusion criteria: a) a) Other DSM-5 disorders: severe alcohol or cannabis use disorder, all other substances: moderate or severe substance use disorder, severe conduct disorder, evidence of psychotic features or prior psychosis (assessed with the SCID-S); b) severe cognitive impairment (e.g., mental retardation, severe developmental disorders) as evidenced by educational records, parental report and/or clinical impression; c) other circumstances that might affect participation (e.g., severe medical disorder, relocation).

Design outcomes

Primary

Measure	Time frame
Change suicidality as measured with the SIQ-JR, pre-post at baseline, 5.5, 8.5, 11.5 and 17.5 months after baseline.	—

Secondary

Measure	Time frame
The secondary outcomes are (fatal) suicide attempts (SCID-S), depression (SCID-S,PHQ-9, and CDI-2), disability (WHODAS 2.0), family functioning (SRFF), non-suicidal self injury (NSSI), young adult attachment (SBS), entrapment (E-SF), autonomy (My Parents and I: a combination of items van de EAS en de PSI), childhood trauma (CTQ), working alliance (WAI-12), ABFT treatment fidelity (TBRS-3), treatment adherence (TPC), cost-effectiveness and health care costs (EQ-5D-5L, TiC-P). The secondary study parameters will be analysed using Generalized Linear Mixed Modelling with adequate link functions, using all five assessment time points of the primary outcome measure cost-effectiveness analyses.	—

Measure

Time frame

The secondary outcomes are (fatal) suicide attempts (SCID-S), depression (SCID-S,PHQ-9, and CDI-2), disability (WHODAS 2.0), family functioning (SRFF), non-suicidal self injury (NSSI), young adult attachment (SBS), entrapment (E-SF), autonomy (My Parents and I: a combination of items van de EAS en de PSI), childhood trauma (CTQ), working alliance (WAI-12), ABFT treatment fidelity (TBRS-3), treatment adherence (TPC), cost-effectiveness and health care costs (EQ-5D-5L, TiC-P). The secondary study parameters will be analysed using Generalized Linear Mixed Modelling with adequate link functions, using all five assessment time points of the primary outcome measure cost-effectiveness analyses.

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Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)