Premature birth Preterm birth preterm deliver Premature birth Preterm birth preterm deliver
Conditions
Interventions
Sponsors
Amsterdam UMC
Eligibility
Age
16 Years to 64 Years
Inclusion criteria
Inclusion criteria: Women above the age of 16 years with a twin pregnancy and an asymptomatic short cervix or dilatation at routine ultrasound investigation below 24 weeks of pregnancy
Exclusion criteria
Exclusion criteria: - Women with a mono-amniotic twin pregnancy - Women with twin pregnancy in which one or both children are diagnosed with a major structural, congenital or chromosomal abnormality that is likely to influence the composite adverse neonatal outcome. - Women with dilatation of the cervix and signs of clinical intra-uterine infection, defined by the presence of fever >= 38 degrees Celsius. - Women with overt symptoms of preterm labour at time of measurement of short cervix (regular contractions, PPROM, recurrent blood loss). - Women with a placenta previa, defined as a placenta position covering the internal ostium of the cervix. - Women who do not master the Dutch of English language and therefore not able to give written consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome will be extreme PTB | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes include a composite for adverse neonatal outcome, PTB | — |
Countries
Belgium, Denmark, Netherlands
Contacts
Public ContactM.A. Oudijk
Amsterdam UMC
Outcome results
None listed