posttraumatic stress Posttraumatic stress disorder (PTSD)
Conditions
Interventions
None listed
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this cohort, a participant must meet all of the following criteria: - Age 18 years or older; - Experience of an traumatic event according to DSM-5 PTSD A criterion (i.e. involving actual or threatened death, violence or violation of physical integrity) maximally 60 days posttrauma at baseline. - The traumatic events need to be directly experienced by the participant themselves, have an acute onset, external cause and the potential to lead to serious physical injury (i.e. not a medical condition).
Exclusion criteria
Exclusion criteria: A potential participant who meets any of the following criteria will be excluded from participation: - Evidence of homicidality, suicidality, injuries due to intentional self-inflicted injury; - Evidence of ongoing or repeated trauma exposure, such as ongoing domestic violence; - Evidence of an inability to understand study procedures, risks or being otherwise unable to give informed consent; - Evidence of being unable to follow protocol (due to any reason, including visual or cognitive or physical impairment precluding completion of protocol); - Impairment in ability to use or no regular access to internet-connected smartphone, tablet or computer for completion of online assessments; Insufficient understanding of Dutch language to follow protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the Area under the Receiver Operator Characteristic curve (AUC) of the derived machine learning algorithms, reflecting the accuracy in correctly classifying participants in the respective test sets into the adverse latent PTSD symptom trajectories. These adverse latent PTSD symptom trajectories are determined from the PTSD symptom severity measured across assessments (TraumaTIPS: CAPS total score, 2-ASAP: PCL5 total score). The machine learning algorithms are based on information collected from self-report questionnaires at the baseline assessments, relating to demographic characteristics, details on current and previous trauma exposure and related emotions, cognitions and social support and current and immediate past psychological and physical health symptoms. | — |
Secondary
| Measure | Time frame |
|---|---|
| The baseline assessment additional includes current best-practice screening instruments for PTSD (secondary outcomes). The follow-up assessments additionally includes self-report questionnaires on co-morbid psychological symptoms and functional and economic outcomes (secondary outcomes). | — |
Countries
Netherlands
Outcome results
None listed