stoppen/ starten/ dosisaanpassing van medicatie bij acuut zieke sarcopene geriatrische patienten met polyfarmacy en diverse uitgebreide co-morbiditeit waarbij de betrokken aandoeningen heel divers kunnen zijn en de reden van de medicatie wijziging ook verschillend kan zijn. medication adjustment in older frail hospitalized patients with low muscle strength and muscle mass using at least 5 different medications. (de)prescribing in acutely ill hospitalized sarcopenic geriatric patients with polyp
Conditions
Interventions
Medication review in patients randomised to the IG group will be performed
according to the principles of DPA and in the CG this will be performed
following the SSA approach.
Sponsors
Zuyderland Medisch Centrum
Eligibility
Age
65 Years to 99 Years
Inclusion criteria
Inclusion criteria: frail older adults, 70 Y and older with sarcopenia and polypharmacy admitted to the acute care hospital ward because of an acute medical problem
Exclusion criteria
Exclusion criteria: If a patient is not instructable. If a patient has an implantable cardioverter defibrillator (ICD) or no informed consent or if there is no (legal) representative with informed consent if the patient is (temporary) incapacitated. Patients in a palliative phase will be excluded from this study, since most medication will be stopped in a palliative setting. Finally, patients with an expected admission time of less than 48 hours will be excluded due to logistic reasons (48 hours are needed to screen for suitability, minimum of 24 hours to consider participation).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| number and type of medication stopped during medication review and not restarted within 1, 3 and 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints: number and severity of Adverse Drug Reactions (ADR) and complications due to medication (e.g. delirium or falls), hospital readmission, quality of life (QoL) and mortality | — |
Countries
Netherlands
Outcome results
None listed