Translabyrinthine acquisition of human adult cochlear tissue for molecular and cellular characterisation of the human cochlea

Translabyrinthine acquisition of human adult cochlear tissue for molecular and cellular characterisation of the human cochlea - Molecular and cellular characterisation of the human cochlea

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON53687

Enrollment

Registered

2023-01-05

Start date

2024-02-09

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

1. Normal inner ear. 2. Deafness

Interventions

Additional acquisition of cochlear tissue.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - A planned translabyrinthine approach, part of standard medical care - Preoperative good or residual hearing at the affected side - Age 18 years and over, who have mastered the Dutch or English language

Exclusion criteria

Exclusion criteria: Mentally incapacitated

Design outcomes

Primary

Measure	Time frame
RNA and protein expression profiles and morphology analysis of the human cochlea compared to inner ear organoids.	—

Countries

Netherlands

Contacts

Public ContactH Locher

Leids Universitair Medisch Centrum

KNO-onderzoek@lumc.nl0715262434

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)