An explorative and experimental study to assess the feasibility, acceptability and effectiveness of four imagery intervention techniques in the treatment of auditory vocal hallucinations

An explorative and experimental study to assess the feasibility, acceptability and effectiveness of four imagery intervention techniques in the treatment of auditory vocal hallucinations - Imagery interventions for auditory vocal hallucinations

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON53589

Enrollment

Registered

2022-02-14

Start date

2022-04-07

Completion date

Unknown

Last updated

2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Auditory vocal hallucinaties hearing voices

Interventions

This protocol consists of four different studies assessing four imagery intervention techniques (metacognitive imagery intervention, imagery rescripting, promoting positive imagery and competing ima

Eligibility

Age

16 Years to 64 Years

Inclusion criteria

Inclusion criteria: • Age 16-65 • Experiencing subclinical or clinical psychotic auditory vocal hallucinations as confirmed by a clinician and as indicated by an intensity score of 4 or more on subscale 1.3 (perceptual abnormalities) of the Comprehensive Assessment of At Risk Mental States (CAARMS; Yung et al., 2005) or as indicated by a score of 3 or more on item P3 (hallucinatory behavior) of the Positive and Negative Syndrome Scale (PANSS; Kay, Fiszbein, & Opler, 1987). • A DSM-5 (APA, 2013) diagnosis in the psychosis spectrum (codes: DSM-5 codes: 297.1; 298.8; 295.40; 295.90; 295.70; 298.8; 298.9) or defined as Ultra High Risk/At Risk Mental State (ARMS or UHR) according to the CAARMS estimated by a clinician.

Exclusion criteria

Exclusion criteria: • Any current or previous neurological disorder or organic brain disease. • Acute confusional state or delirium not caused by the psychotic disorder. • Unwillingness to participate • IQ < 70 estimated by clinician. • Current severe substance or alcohol misuse impacting treatment (clinicians assessment).

Design outcomes

Primary

Measure	Time frame
The primary outcome variables are the level of auditory vocal hallucinations, imagery characteristics (imagery frequency, imagery appraisals and imagery quality) measured three times a day using a diary method, and feasibility and acceptability measures (adverse (side) effects, drop-out rates and qualitative review of therapy).	—

Secondary

Measure	Time frame
The secondary outcomes are the level delusions, visual hallucinations and social and occupational functioning measured three times a day using a diary method.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)