Neurodevelopmental Outcomes and Morbidities of Moderate and Late Preterm Children at the Age of 9 Years - The Alkmaar MLPTI Cohort Study

Neurodevelopmental Outcomes and Morbidities of Moderate and Late Preterm Children at the Age of 9 Years - The Alkmaar MLPTI Cohort Study - The Alkmaar MLPTI Cohort study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON53576

Enrollment

155

Registered

2022-07-21

Start date

2023-08-11

Completion date

Unknown

Last updated

2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

premature birth/ Preterm birth

Interventions

nvt

Eligibility

Age

2 Years to 11 Years

Inclusion criteria

Inclusion criteria: 1. The participant is born in or transferred to the NWZ Alkmaar between January 1st, 2014 and April 18th, 2016 (the inclusion time of trial NL50800.094.14) 2. The participant born at a gestational age from 32 to 35+6 weeks 3. The participant received follow-up conform the trial with trial-number NL50800.094.14 4. Both parents of the participant have given informed consent to participate in this trial OR (Control group) 1. The participant has a brother, sister or friend who meets aforementioned inclusion criteria. 2. The participant is between 8 and 10 years old when participating in this study. 3. The participant is a child that lives

Exclusion criteria

Exclusion criteria: 1. The participant*s parents are not able to fill out questionnaires or perform tests in Dutch 2. The participant has a severe developmental disorder and is thereby not able to perform the tests 3. The participant is not able to come to the outpatient clinic to do the tests OR (Control Group) 1. The participant is born with a GA

Design outcomes

Primary

Measure	Time frame
The main study parameters are the IQ-scores, motoric scores of the M-ABC, executive functions of the EMMA Toolbox and speech- and language-developmental scores of the CELF-5-NL and CCC-2-NL.	—

Secondary

Measure	Time frame
Secondary outcome parameters are CITO-scores, the behavioural and psychosocial outcomes of the CBCL and the SDQ, the presence of morbidities, the growth pattern and blood pressure. Other outcome parameters are the relation between the 9-year outcomes and the BSID-III scores at the age of 2, and the differences between the MLPTI and the control group. Furthermore, we aim to determine the relation between growth and body composition in the first two years of life and the waist circumference, growth parameters and blood pressure at the age of 9 years.	—

Measure

Time frame

Secondary outcome parameters are CITO-scores, the behavioural and psychosocial outcomes of the CBCL and the SDQ, the presence of morbidities, the growth pattern and blood pressure. Other outcome parameters are the relation between the 9-year outcomes and the BSID-III scores at the age of 2, and the differences between the MLPTI and the control group. Furthermore, we aim to determine the relation between growth and body composition in the first two years of life and the waist circumference, growth parameters and blood pressure at the age of 9 years.

—

Countries

Netherlands

Contacts

Public ContactF de Groof

Noordwest Ziekenhuisgroep

f.de.groof@nwz.nl0725484444

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Jul 23, 2026