niet medische problemen met darmfunctie (stoelgang) bowel function issues defecation problems difficulty to have bowel movements
Conditions
Interventions
A vegetable product consisting of dried chicory root cubes containing 85%
dietary fibre is added to the daily diet. The intervention product is consumed
twice daily for four weeks with a maximum dos
Sponsors
Wageningen Universiteit
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: • 20 - 80 years old • Unsatisfied with bowel habits (self-reported), rated on a visual analogue scale (VAS, 0-10) as
Exclusion criteria
Exclusion criteria: • Having a history of medical or surgical events that may significantly affect the study outcome: IBS or IBD patients and subjects with medically diagnosed constipation (i.e. constipation related to anatomic, medication-related, or readily identifiable physiological causes.) • Less than one bowel movement per week during the screening period. • Medical drug use: o Antibiotic use within 3 months of the screening o Chronic use of antacids and PPI*s o Use of laxatives 1 month during the screening o Chronic use of blood glucose lowering medication • Consumption of supplements containing fibres (other than laxatives), pro-/ post-/ synbiotics 1 month before the screening • Unable to comply with proper study procedures • Not willing to provide faecal samples • For women of childbearing age: current or planned pregnancy, lactation • Known allergic reactions to plants from the Asteraceae (Compositae) family (e.g. lettuce, daisies, sunflowers, artichokes, sage, tarragon, chamomile, chicory etc.) • Reported unexplained weight loss or weight gain of > 5 kg in the month prior to screening • Reported slimming or medically prescribed diet or macrobiotic life-style • Personnel the Division of Human Nutrition & Health or the Laboratory of Microbiology • Current participation in other medical scientific research • Not having a general practitioner • Not willing to be informed about accidental discoveries in relation to the subjects health
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare four-week differences in bowel function assessed by stool frequency, stool consistency, ease of defecation, feeling of incomplete bowel emptying and bowel habit satisfaction between subjects with bowel function issues consuming either 15 g/day dried chicory root particles or placebo (rice puff crisp particles). | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare four-week differences in bowel function assessed by stool frequency, stool consistency, ease of defecation, feeling of incomplete bowel emptying and bowel habit satisfaction and gut microbiota and its activity, quality of life, constipation symptom assessment between subjects with bowel function issues consuming three different dosages dried chicory root particles or placebo (rice puff particles). Furthermore, to compare four-week evolution of bowel function, gut microbiota and its activity over time in subjects with bowel function issues consuming dried chicory root particles or placebo. | — |
Countries
Netherlands
Outcome results
None listed