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MRI Exploration of Protein Digestion

MRI Exploration of Protein Digestion - MOVE

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON53523
Enrollment
12
Registered
2023-04-04
Start date
2023-05-01
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

fysiologie van eiwit vertering NA (er wordt geen aandoening bestudeert)

Interventions

None listed

Sponsors

Wageningen Universiteit
Lead Sponsor

Eligibility

Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: 18-45 years old Apparently healthy Normal weight (BMI 18.5-25 kg/m2)

Exclusion criteria

Exclusion criteria: • Milk protein allergy or intolerance y (self-reported) • Lactose intolerance (self-reported) • Gastric disorders or regular (>once a week) gastric complaints such as heartburn • Use of medication which alters the normal functioning of the stomach, such as: - medical drug use that influences the GI tract*s normal function, e.g. the motility, pH etc: among others use of proton pump inhibitors, antacids, anti-depressants etc. • Being pregnant, lactating or planning on becoming pregnant during the study • Use of recreational drugs within one week prior to the test day (marihuana, XTC, GHB, helium) • Alcohol consumption of more than 7 glasses/per week • Smoking (>2 cigarettes a week) • Having gained or lost more than 5 kg weight in the last month. • Participating in other biomedical research during the study period • Having a contra-indication to MRI scanning (including, but not limited to): - Intraorbital or intraocular metallic fragments - Ferromagnetic implants - Claustrofobia (self-reported) • Unwillingness to be referred to my general practitioner in case of a chance finding of pathology • Being an employee or thesis student of the Division of Human Nutrition and Health or the Laboratory of Biophysics at Wageningen University.

Design outcomes

Primary

MeasureTime frame
1. Average MTR of the stomach content over time (a measure of semi-solid protein content)

Secondary

MeasureTime frame
1. Average CESTR of the stomach content over time (a measure of soluble protein/peptide content)

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)