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Verb processing and word learning in DLD: Diagnostic tests and neural correlates

Verb processing and word learning in DLD: Diagnostic tests and neural correlates - Language and brain development in children with DLD

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON53457
Enrollment
100
Registered
2023-01-30
Start date
2023-03-03
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

taalontwikkelingsstoornissen 'developmental language disorder' and 'specific language impairment'

Interventions

None listed

Sponsors

Rijksuniversiteit Groningen
Lead Sponsor

Eligibility

Age
2 Years to 15 Years

Inclusion criteria

Inclusion criteria: Children with a developmental language disorder (DLD): - 8 to 12 years of age - Attend special education (cluster 2 education) permanently or remotely - Diagnosed with DLD by a licensed professional Typically developing children: - 8 to 12 years of age - Attending regular education

Exclusion criteria

Exclusion criteria: Children with DLD: - History of neurodevelopmental disorders - History of psychiatric illness - Recent use (within 1 week) of any psychopharmaceutic drug - Intellectual disability - Severe articulatory difficulties - Uncorrected vision or hearing impairment Typically developing children: - A diagnosis of DLD or suspected DLD - History of neurodevelopmental disorders - History of psychiatric illness - Recent use (within 1 week) of any psychopharmaceutic drug - Intellectual disability - Severe articulatory difficulties - Uncorrected vision or hearing impairment

Design outcomes

Primary

MeasureTime frame
For the primary objective 1, the main MRI parameters are cortical thickness and white matter integrity (mean diffusivity, radial diffusivity, and fractional anisotropy). The main behavioral parameters are the scores on the verbal learning tasks. For objectives 2 and 3, the main parameters are the scores on the newly developed tasks of the verb battery.

Secondary

MeasureTime frame
Demographic information (age, gender, parental educational level, mono/bi/multilingual language background) and general language or cognitive information (nonverbal IQ, auditory discrimination, word reading with Eén Minuut Test (EMT) and non-word reading with Klepel test) will be summarized and reported using descriptive statistics. Furthermore, scores in the CCC-2-NL questionnaire will be used to signal if any of the children recruited for the TD group presents with a profile indicative of language impairment. If so, or if the nonverbal IQ scores are outside the normal range, those children*s data will not be included in the study.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)