taalontwikkelingsstoornissen 'developmental language disorder' and 'specific language impairment'
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Children with a developmental language disorder (DLD): - 8 to 12 years of age - Attend special education (cluster 2 education) permanently or remotely - Diagnosed with DLD by a licensed professional Typically developing children: - 8 to 12 years of age - Attending regular education
Exclusion criteria
Exclusion criteria: Children with DLD: - History of neurodevelopmental disorders - History of psychiatric illness - Recent use (within 1 week) of any psychopharmaceutic drug - Intellectual disability - Severe articulatory difficulties - Uncorrected vision or hearing impairment Typically developing children: - A diagnosis of DLD or suspected DLD - History of neurodevelopmental disorders - History of psychiatric illness - Recent use (within 1 week) of any psychopharmaceutic drug - Intellectual disability - Severe articulatory difficulties - Uncorrected vision or hearing impairment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| For the primary objective 1, the main MRI parameters are cortical thickness and white matter integrity (mean diffusivity, radial diffusivity, and fractional anisotropy). The main behavioral parameters are the scores on the verbal learning tasks. For objectives 2 and 3, the main parameters are the scores on the newly developed tasks of the verb battery. | — |
Secondary
| Measure | Time frame |
|---|---|
| Demographic information (age, gender, parental educational level, mono/bi/multilingual language background) and general language or cognitive information (nonverbal IQ, auditory discrimination, word reading with Eén Minuut Test (EMT) and non-word reading with Klepel test) will be summarized and reported using descriptive statistics. Furthermore, scores in the CCC-2-NL questionnaire will be used to signal if any of the children recruited for the TD group presents with a profile indicative of language impairment. If so, or if the nonverbal IQ scores are outside the normal range, those children*s data will not be included in the study. | — |
Countries
Netherlands