cerebral palsy cerebral palsy
Conditions
Interventions
N.A.
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
No minimum to 11 Years
Inclusion criteria
Inclusion criteria: -All infants with confirmed brain injury on MRI at high risk for cerebral palsy. -Written informed parental consent (Dutch, English, French, German, Italian, Spanish).
Exclusion criteria
Exclusion criteria: -Infants not matching the inclusion criteria -Any proven or suspected severe congenital anomaly, genetic or metabolic disorder -Presence of an infection of the central nervous system -Parents
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The creation of a ML algorithm (including standard clinical care assessment: MRI, EEG, and clinical data collected up to 3 months of age, including GMA and HINE) being able to early predict motor, behavioral, cognitive outcome. The creation and implementation of automated tools to analyze these early assessments in at-risk infants to obtain a more precise, individualized diagnosis and prognosis of CP based on harmonized scans and protocols (GMFCS, BSID-III, CBCL). | — |
Secondary
| Measure | Time frame |
|---|---|
| The development of recommendations to support parents in the process of disclosure of diagnosis and communication around prognosis of the development of their child, using questionnaires and interviews with parents. | — |
Countries
France, Germany, Italy, Netherlands, Spain
Contacts
Public ContactM.L. Tataranno
Universitair Medisch Centrum Utrecht
Outcome results
None listed