sexual (dys)function sexual (dys)functioning
Conditions
Interventions
None listed
Sponsors
Amsterdam UMC
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: - Adult, >18 years of age - Able to give written informed consent - Having a primarily heterosexual orientation - Having a stable, sexually active relationship for at least the preceding 6 months In addition, for premenopausal women: - Age 45 years, and no menstruation since at least one year, after a previously regular menstrual cycle. No use, or recent (in the prior 6 months) use of estrogen, hormonal medication, or hormonal contraception.
Exclusion criteria
Exclusion criteria: - Use, or recent (in the prior 6 months) use, of psychotropic medication - Acute or chronic medical or mental conditions with a known effect on sexual response - Current pregnancy or delivery within the last 12 months - History of hysterectomy or vaginal surgery, gynecologic disease or malignancy, pelvic inflammatory disease or vaginal infection and known anatomical abnormalities of the genitalia. - Contra-indications to MRI (metal implants, pacemakers, claustrophobia, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is clitoral volume during sexual arousal assessed by MRI in healthy pre and postmenopausal women. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints are self-reported feelings of sexual arousal during audiovisual sexual stimulation (erotic film), and sexual function assessed by a validated sexual function questionnaire with the addition of items about orgasmic functioning. | — |
Countries
Netherlands
Outcome results
None listed