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IMPROVE - improving anxiety treatments by modulating emotional memories prior to in vivo exposure: a multiple baseline study

IMPROVE - improving anxiety treatments by modulating emotional memories prior to in vivo exposure: a multiple baseline study - IMPROVE: improving anxiety treatments

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON53388
Enrollment
8
Registered
2023-07-06
Start date
2024-06-01
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Social anxiety (anxiety in social situations)

Interventions

A standardized intervention will be used: EMDR therapy. The same intervention was used in a randomized controlled trial in social anxiety disorder (NL73918.041) that was terminated prematurely due t

Sponsors

Universiteit Utrecht
Lead Sponsor

Eligibility

Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: - Patients >=18 years of age - Sufficient mastery of the Dutch language and ability to complete questionnaires and understand informed consent information - Meeting DSM-5 criteria for social anxiety disorder (assessed with MINI-S-DSM-5). - Stable medication for at least six weeks before starting participation in the study and willingness by the patient and physician to keep the medication stable during the study period. The use of sedating medication (e.g. benzodiazepines) is no contraindication however, participants are strongly advised not to use sedating medication prior to- or after treatment sessions and subsequent days. The use of sedating medication will be registered - Self-reported ability to refrain from alcohol or drugs 24 hours before and after each session. General use of alcohol or drugs will be discouraged.

Exclusion criteria

Exclusion criteria: - Self-reported neurological disorder - Acute or recent history of suicide attempts according to the (MINI-S-DSM-5) section C - Self-reported visual or auditory impairments that could hinder treatment - Self-reported current psychological treatment for other DSM-5 disorders - Being reluctant or unable to complete questionnaires online

Design outcomes

Primary

MeasureTime frame
Primary outcomes are: 1. social anxiety symptoms. 2. Social avoidance symptoms.

Secondary

MeasureTime frame
Secondary outcomes are: Weekly social anxiety symptom severity.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Jun 27, 2026