sugar Type 2 diabetes mellitus Type 2 diabetes mellitus
Conditions
Interventions
During the 14 days of monitoring, participants are asked to undergo one OGTT
and consume a standardized snack (Snelle Jelle) twice after an overnight fast.
In between, the participants are asked to
Sponsors
TNO
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - - Diagnosed with (pre)diabetes type 2; o BMI >=27 kg/m2, including a heterogenous group of people with overweight/prediabetes (without glucose lowering medication), and/or type 2 diabetes with or without glucose lowering medication. - Aged 40 years or older - Able and willing to sign the informed consent form - Willing to comply with all study procedures
Exclusion criteria
Exclusion criteria: - Type 1 diabetes - Latent Autoimmune Diabetes (LADA) - Skin allergy, eczema or known sensitivity for adhesives - History of bariatric weight loss surgery - Planned (bariatric) surgery during the 3 weeks monitoring period with the CGM - Active cancer or chemotherapy or radiation within 2 years prior to participation - A condition that would need an MRI during the 3 weeks monitoring period with the CGM - Planned holiday during the 3 week GCM monitoring period - (Night)shiftworkers - Pregnancy and lactation - Chronic medical condition, treatment, or medication other than diabetes that may affect glucose metabolism (HIV diagnosis, use of steroids or immunosuppressive drugs, etc.) - 4 or more alcoholic drinks per day on a regular basis or use of recreational drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The objective of this study is to develop and evaluate algorithms predicting the different diabetypes and the underlying indices (diabetyping) with minimally invasive technology based on capillary sampling using and multi-day CGM with OGTT. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary objective is to develop and evaluate minimally invasive diabetyping technology with algorithms based on capillary sampling, venous blood sampling and multi-day CGM upon a standardized snack under real-world conditions. | — |
Countries
Netherlands
Contacts
Public ContactR.J.M. Kamstra
TNO
Outcome results
None listed