Atopic dermatitis eczema
Conditions
Interventions
None listed
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
2 Years to 11 Years
Inclusion criteria
Inclusion criteria: - Children aged 7 to 11 years, with atopic dermatitis (AD diagnosed according to the UK working party criteria) - Child and parent(s)/legal guardian(s) having sufficient comprehension of the Dutch language to understand study materials - Children and parents/guardians able to participate in the study and willing to give written informed consent
Exclusion criteria
Exclusion criteria: - Children under the age of 7 or above the age of 11 years - Children with large burn scars or other large scars - Children with chicken-pox or other infections that cause skin itch or pain - Children with itch without visible dermatological abnormalities (pruritus sine materia, e.g.renal failure (acute, chronic), hyperthyroidism, Hodgkin disease) - Children with genetic syndromes known to affect cognitive performance - Children with an IQ estimated
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is sustained attention measured with the Amsterdamse Neuropsychologische Taken (ANT) Sustained Attention Dots subtest. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are observations of task-oriented behavior and itch-related behavior (e.g. scratching), tests of interoceptive accuracy, interoceptive awareness, cutaneous sensibility, and thermal (cold and warm) and vibration detection thresholds, questionnaires on sensory processing modulation, emotional and behavioral problems, quality of life, and itch, and physician reported AD severity. | — |
Countries
Netherlands
Outcome results
None listed