opname van aminozuren amino acid uptake kinetics digestion and uptake
Conditions
Interventions
During each visit, research subjects will receive one of the six protein blends
(whey protein, casein protein, faba protein, pea protein, pea protein + casein
protein, pea protein + methionine) diss
Sponsors
FrieslandCampina (FC C.V.)
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: • Apparently healthy men and women; • Age >=18 and =18.5 and
Exclusion criteria
Exclusion criteria: • Any self-reported metabolic, gastrointestinal, inflammatory or chronic disease (such as anemia, diabetes, hepatitis, cardiovascular disease); • Having a history of medical or surgical events that may significantly affect the study outcome, including: Inflammatory bowel disease, hepatitis, pancreatitis, ulcers, gastrointestinal or rectal bleeding; major gastrointestinal tract surgery such as gastrectomy, gastroenterostomy, or bowel resection; known or suspected gastrointestinal disorders, colon or GI tract cancer; • Anaemia (Haemoglobin (Hb) values 3 kg in the month prior to pre-study screening, or intention to lose weight during the study period; • Reporting to follow or having planned a slimming or medically prescribed diet. • Not willing to keep a stable lifestyle during the study period; • Recent blood donation (21 (women) or >28 (men) glasses of alcoholic beverages per week; • Use of drugs; • Current smokers; • Pregnant, lactating or wishing to become pregnant in the period of the study (self-reported); • Not having a general practitioner; • Insufficient proficiency in Dutch to understand information brochure and questionnaires; • Participation in any clinical trial including blood sampling and/or administration of substances up to 30 days before test day 1 of this study; • Being an employee of the department Food, Health & Consumer Research of Wageningen Food & Biobased Research or FrieslandCampina R&D.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the postprandial profile (iAUC and peak Cmax) of total essential amino acids (TEAA) before and after consumption of pea, faba, casein, and whey. | — |
Secondary
| Measure | Time frame |
|---|---|
| Other study parameters include total and individual (essential) amino acid profiles (iAUC, peak Cmax, and Time-2-max) before and after consumption of pea, pea+methionine, pea+casein, faba, casein, and whey. | — |
Countries
Netherlands
Outcome results
None listed