brain tumor glioma
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Patient with suspected glioma, i.e. low- or high-grade gliomas. - Age older than 18 years - Sufficient command of the Dutch language - Being able to understand the instructions of the neuropscyhological assessment and to mentally and physically sustain/endure the assessment; this will be assessed in a consultation between treating physician (neurosurgeon) and investigator (neuropsychologist).
Exclusion criteria
Exclusion criteria: - Serious neurodegenerative or psychiatric conditions (including addiction) - Serious (other) medical conditions or physical inability hindering patients to come to the hospital - Patients who need to undergo emergency craniotomy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters are outcomes on measures for social cognition and language. Social cognition measures: - The Ekman 60 faces test of the Facial Expressions of Emotion Stimuli and Tests (emotion recognition) - Cartoons test (ToM) - Faux Past test (ToM, affective empathy). Measures for language: - letter and category fluency (verbal fluency, executive control) - shortened version of the Boston Naming Test (visual confrontation naming) - ScreeLing (screening of linguistic deficits) - subtest of the Semantische Afasie Nederland (SAN) test (language comprehension). | — |
Secondary
| Measure | Time frame |
|---|---|
| Patients To assess spontaneous and general language, the following measurements will be used: * The Cookie Theft Picture Test * Story telling (Fairy Tale and Christmas story) * QuEST-NL Patients and proxies Three questionnaires will be used to examine social abilities and interaction: * Interpersonal Reactivity Index (IRI) - empathy * Dysexecutive Questionnaire (DEX) - difficulties in everyday situations * Couples Satisfaction Index (CSI) - relationship satisfaction Other study parameters: Demographic data (including age, gender and education level) and information regarding tumor characteristics (classification of tumor type, tumor location, molecular mutations) will be obtained from the patient's medical reports. Furthermore, general cognitive abilities will be measureds using the following tests, allowing to control for severe cognitive impairment that may interfere with the performance on tests for social cognition and language. * Rivermead Behavioral Memory Test (RBMT) - verbal memory * Rule Shift Cards Test - cognitive flexibility | — |
Countries
Netherlands
Outcome results
None listed