Borstsamenstelling tijdens zwangerschap, lactatie en post-lactatie breastfeeding problems lactation insufficiency
Conditions
Interventions
None listed
Sponsors
Universiteit Twente
Eligibility
Inclusion criteria
Inclusion criteria: • Women with a child wish OR in the first trimester of pregnancy • Between 18 to 45 years • >9 months postpartum & post breast feeding of previous pregnancy
Exclusion criteria
Exclusion criteria: • Breast augmentation, reduction, reconstruction or other procedures • Breast tattoos or piercings • Known breast disease at time of the experiment • Pregnancy or breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| This study aims to map the spatiotemporal changes in the anatomical and physiological parameters of the human lactating breast from pregnancy to post-lactational involution. The main study parameters are the amount of glandular and adipose tissue of the breast and the blood content of the breast, as well as a one-time 24h milk production measurement 4 to 6 weeks postpartum. | — |
Secondary
| Measure | Time frame |
|---|---|
| • Validate DOSI against MRI for measuring the amount of glandular and adipose tissue inside the breast • Evaluate the relation between (changes in) breast tissue composition and milk production • Define the duration of post-lactational involution • Compare breast tissue composition before pregnancy to after post-lactational involution | — |
Countries
Netherlands
Outcome results
None listed