Intraoperative hypotension
Conditions
Interventions
The HemoSphere Advanced Monitor with hypotension prediction index (HPI)
software is the investigated product in this research. With the help of the HPI
algorithm, hypotension can be predicted up to
Sponsors
Medisch Spectrum Twente (MST)
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Informed consent - Aged 18 years or older - Planned for moderate- or high-risk elective non-cardiac surgery under general anaesthesia - Need for continues blood pressure monitoring with the help of an arterial line during surgery - Target MAP of 65 mmHg during surgery - Elective surgery
Exclusion criteria
Exclusion criteria: - Target MAP higher or lower than 65 mmHg - Current persistent cardiac arrhythmias, including atrial fibrillation - Liver and vascular surgery with vascular clamping - Hypotension before surgery, defined as MAP
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure is the area under the threshold (AUT) of hypotension (defined as MAP | — |
Secondary
| Measure | Time frame |
|---|---|
| - Incidence of hypotension - Time spend in hypotension - Length of hypotensive episodes - Time weighted average of hypotension - Cross-correlation between MAP values and HPI values - Troponin level before and after surgery - Creatine level before and after surgery - 30-day mortality after surgery | — |
Countries
Netherlands
Contacts
Public ContactJW Potters
Medisch Spectrum Twente (MST)
Outcome results
None listed