Breastfeeding physiology Breastfeeding physiology
Conditions
Interventions
nvt.
Sponsors
University of Twente
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Group I • Lactating women • Between 18 to 45 years • 0.5 to 12 months postpartum Group II • Non-lactating women • Between 18 to 45 years • >9 months postpartum of pregnancy • >9 months post-breastfeeding of pregnancy
Exclusion criteria
Exclusion criteria: Group I • Breast augmentation, reduction, reconstruction or other procedures • Breast tattoos or piercings • Known breast disease at time of the experiment, e.g. mastitis • Problems with breastfeeding at the time of experiment, e.g. mastitis • Pregnancy • Allergy for (medical) tape • Not eligible for MRI, see F1. Vragenlijst Screening MRI. This includes having a: • Pacemaker • Implantable cardioverter-defibrillator (ICD) • Hearing implant • Drug pump • Neurostimulator • Claustrophobia Group II • Breast augmentation, reduction, reconstruction or other procedures • Breast tattoos or piercings • Known breast disease at time of the experiment • Pregnancy • Was pregnant or breastfeeding less than 9 months prior to moment of measurement (due to an expected difference in breast tissue composition) • Allergy for (medical) tape • Not eligible for MRI, see F1. Vragenlijst Screening MRI. This includes having a: • Pacemaker • Implantable cardioverter-defibrillator (ICD) • Hearing implant • Drug pump • Neurostimulator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters are 1) the flow rate and total milk volume produced during one milk extraction with a breast pump and its relation to 2) the amount of glandular and adipose tissue inside the breast, and 3) the hemodynamics inside the breast, which will be studied by (changes in) the oxygen saturation and the available haemoglobin inside breast tissue. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome is the validation of DOSI with MRI for the measurement of the amount of glandular and adipose tissue inside the breast. | — |
Countries
Netherlands
Contacts
Public ContactA Boamfa
University of Twente
Outcome results
None listed