atrial fibrillation
Conditions
Interventions
No investigational products and/or interventions are being tested in this study. This is a prospective cohort study in which investigational procedures and interventions are used to answer scientific
Sponsors
Maastricht Universitair Medisch Centrum +
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Age > 18 years; - Undergoing first elective open chest cardiac surgery; - Able and willing to sign informed consent for the registry; - Able and willing to undergo heart rhythm monitoring with noninvasive recorders.
Exclusion criteria
Exclusion criteria: - Deemed unsuitable or not willing to undergo heart rhythm monitoring with noninvasive recorders or to attend follow-up visits; - Pregnancy; - Life expectancy of less than 2.5 years; - History of prior cardiac surgery or ablation for AF.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Determining genetic, electrical, biochemical, molecular and structural factors in atrial and ventricular biopsies and blood that contribute to AF initiation and progression during 3 years after open heart surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| - AF incidence and duration, - severe cardiovascular and cerebral consequences of AF, - complexity of AF on digital EKG, - AF biomarkers associated with AF progression, - CT and ultrasound parameters predictive of AF progression and duration, - genotyping of different AF types. | — |
Countries
Netherlands
Contacts
Public ContactM.J. Kawczynski
Maastricht Universitair Medisch Centrum +
Outcome results
None listed