Intestinal microbiota, executive functioning and micronutrient status in enduring anorexia nervosa: a pilot study

Intestinal microbiota, executive functioning and micronutrient status in enduring anorexia nervosa: a pilot study - Microbiota in enduring anorexia nervosa

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON53103

Enrollment

Registered

2016-12-23

Start date

2018-05-17

Completion date

Unknown

Last updated

2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anorexia nervosa

Interventions

None listed

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: -enduring anorexia nervosa (at least two year continuous presence) according to DSM-5 criteria -age between 18 and 60 years

Exclusion criteria

Exclusion criteria: -renal failure -liver disease -chronic diarrhea -current laxative use -smoking > 5 cigarettes/day -alcohol intake > 10.0 g/day (equals one standard glass alcohol) -current use of multivitamins -pregnancy -IQ below 85

Design outcomes

Primary

Measure	Time frame
Intestinal microbiota: Bacterial DNA will be extracted from stool samples. Neuropsychological Tasks (Executive functions): Wisconsin Card Sorting Test (WCST), Trail Making Test (TMT), Go/No Go task, Iowa Gambling Task (IGT). Questionnaires (Executive functions): Behavior Rating Inventory of Executive Function Adult Version (BRIEF-A-SR), Dickman Impulsivity Inventory (DII). Micronutrient status: Vitamin B1, vitamin B6, vitamin B12, vitamin D, folic acid, magnesium and zinc.	—

Measure

Time frame

Intestinal microbiota: Bacterial DNA will be extracted from stool samples. Neuropsychological Tasks (Executive functions): Wisconsin Card Sorting Test (WCST), Trail Making Test (TMT), Go/No Go task, Iowa Gambling Task (IGT). Questionnaires (Executive functions): Behavior Rating Inventory of Executive Function Adult Version (BRIEF-A-SR), Dickman Impulsivity Inventory (DII). Micronutrient status: Vitamin B1, vitamin B6, vitamin B12, vitamin D, folic acid, magnesium and zinc.

—

Secondary

Measure	Time frame
Eating disorder psychopathology: Eating Disorder Examination Questionnaire (EDE-Q) Depressive symptoms: Inventory of Depressive Symptomatology (IDS-SR) IQ: Nederlandse Leestest voor Volwassenen Food intake: dietary history with check/crosscheck (food diary during three days)	—

Countries

Netherlands

Outcome results