Organic mitral regurgitation (MR): genetic analysis, morphological and tissue characterization.

Organic mitral regurgitation (MR): genetic analysis, morphological and tissue characterization. - Genetic, morphological and tissue analysis in organic MR: "MRgen"

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON53095

Enrollment

300

Registered

2017-04-06

Start date

2017-05-04

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mitral valve prolapse mitral valve regurgitation

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: patients > 18 years, referred to the LUMC for mitral valve repair for organic mitral regurgitation

Exclusion criteria

Exclusion criteria: patiente with syndromal heart disease, mentally disable, active endocarditis

Design outcomes

Primary

Measure	Time frame
Differences between Barlow and FED: - macroscopic: echocardiography - microscopic: mitral valve tissue analysis - familial distribution through pedigree analysis - genetic abnormalities through DNA analysis See pages 16-19 of the Protocol	—

Countries

Netherlands

Outcome results